Across TCGA patient cohorts, NRN1L mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NRN1L-associated genes across cancer lineages are FAM41AY1, TRAPPC2P8, and MTCO3P30. Each is linked with NRN1L in more than 1 cancer types. Because this analysis shows association rather than direction, both NRN1L-to-partner and partner-to-NRN1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRN1L→partner) and Y-score (partner→NRN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FAM41AY1 →	+0.074	+7.741	<.001	.009	3	1
COAD	TRAPPC2P8 →	+0.164	+7.741	<.001	.009	3	1
COAD	MTCO3P30 →	+0.099	+7.741	<.001	.009	3	1
COAD	LINC02286 →	+0.205	+7.741	<.001	.009	3	1
UCEC	MIR4682 →	+0.551	+3.204	.002	.006	3	1
UCEC	RNA5SP124 →	+0.466	+2.996	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

NRN1L survival (RNA) · tumor vs normal (RNA) · all NRN1L data types