Q-omics provides the consensus-scored FAM41AY1 profile across patient tissues and cancer cell-line models. FAM41AY1 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in KIRP. Additionally, FAM41AY1 RNA expression shows 518 significant mutation-linked associations, with the highest sampling consensus in STAD. Together, these results highlight KIRP, and STAD as cancer lineages where FAM41AY1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes FAM41AY1 survival associations across molecular data types. FAM41AY1 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

FAM41AY1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	KIRP (81)	view →

This table ranks reproducible FAM41AY1 RNA expression–survival associations across cancer types. High FAM41AY1 expression shows unfavorable associations in KIRP, BRCA, ESCA and UCEC, but favorable associations in STAD. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for FAM41AY1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.161	0.904	<.001	81	view →
BRCA	OS	Tertile	All	0.115	0.578	.007	72	view →
STAD	DFS	Tertile	All	1.000	0.385	.009	42	view →
ESCA	DFS	Tertile	All	0.044	0.536	<.001	36	view →
UCEC	DFS	Tertile	All	0.168	0.838	<.001	18	view →

Pink = unfavorable, green = favorable. all 5 lineages →

FAM41AY1-KIRP (OS)

Kaplan–Meier survival curve for FAM41AY1 RNA expression in KIRP: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with FAM41AY1 in patient tissues and cancer cell lines. In patient samples, FAM41AY1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Mutation	518	STAD (240)	view →
RNA	247	LUSC (117)	view →