NRIP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NRIP2 mutation is significantly associated with the RNA expression of many other genes, with 1,292 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NRIP2-associated genes across cancer lineages are SNORD116-3, RNA5SP389, and MIR873. Each is linked with NRIP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NRIP2-to-partner and partner-to-NRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-3 grouped by NRIP2-low versus NRIP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRIP2→partner) and Y-score (partner→NRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSNORD116-3 →+0.564+3.992.001.00633
SKCMRNA5SP389 →+0.223+4.614<.001.00632
SKCMMIR873 →+0.329+4.614<.001.00632
UCECPSMC1P2 →+0.138+2.294<.001.00332
UCECMIR6075 →+0.308+2.790.001.00232
BLCAMTND5P21 →+0.113+5.038<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,292 associations by consensus.

SNORD116-3 by NRIP2 expression — SKCM

Box plot of SNORD116-3 in NRIP2-low vs NRIP2-high samples in SKCM.

Explore this box plot interactively →

Exploration