NRGN

Across TCGA patient cohorts, NRGN protein abundance is significantly associated with the protein abundance of many other proteins, with 25,120 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NRGN-associated proteins across cancer lineages are DPYSL2, C11orf96, and CNRIP1. Each is linked with NRGN in more than 6 cancer types. Because this analysis shows association rather than direction, both NRGN-to-partner and partner-to-NRGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NRGN versus DPYSL2 in UCEC, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NRGN→partner) and Y-score (partner→NRGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DPYSL2 →	+0.509	+0.771	<.001	<.001	3	7
UCEC	C11orf96 →	+0.480	+0.497	<.001	<.001	3	6
UCEC	CNRIP1 →	+0.880	+0.786	<.001	<.001	3	6
COAD	MTX1 →	-0.274	-0.667	.003	<.001	3	5
UCEC	CAVIN1 →	+0.913	+0.672	<.001	<.001	3	5
UCEC	CAVIN3 →	+0.855	+0.579	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,120 associations by consensus.

NRGN vs DPYSL2 — UCEC

Explore this scatter interactively →