NRG1-IT3

Across TCGA patient cohorts, NRG1-IT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,908 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NRG1-IT3-associated GO terms across cancer lineages are Regulation of cellular ketone metabolic process, Regulation of steroid metabolic process, and ATP synthesis coupled electron transport. Each is linked with NRG1-IT3 in more than 4 cancer types. Because this analysis shows association rather than direction, both NRG1-IT3-to-partner and partner-to-NRG1-IT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cellular ketone metabolic process grouped by NRG1-IT3-low versus NRG1-IT3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRG1-IT3→partner) and Y-score (partner→NRG1-IT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of cellular ketone metabolic process →	+0.081	+0.064	<.001	.001	3	5
STAD	Regulation of steroid metabolic process →	+0.078	+0.062	<.001	<.001	3	5
STAD	ATP synthesis coupled electron transport →	+0.193	+0.045	<.001	<.001	3	5
STAD	Electron transport chain →	+0.174	+0.045	<.001	<.001	3	4
STAD	Sphingolipid biosynthetic process →	+0.098	+0.075	<.001	.003	3	4
STAD	Positive regulation of transmembrane transport →	+0.073	+0.048	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,908 associations by consensus.

Regulation of cellular ketone metabolic process by NRG1-IT3 expression — STAD

Explore this box plot interactively →