NRG1-IT1

Across TCGA patient cohorts, NRG1-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,756 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NRG1-IT1-associated GO terms across cancer lineages are Mitochondrial gene expression, rRNA metabolic process, and Positive regulation of DNA repair. Each is linked with NRG1-IT1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NRG1-IT1-to-partner and partner-to-NRG1-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by NRG1-IT1-low versus NRG1-IT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRG1-IT1→partner) and Y-score (partner→NRG1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.099	+0.086	<.001	<.001	3	17
STAD	rRNA metabolic process →	+0.100	+0.082	<.001	<.001	3	16
STAD	Positive regulation of DNA repair →	+0.083	+0.089	<.001	<.001	3	15
STAD	Amino acid activation →	+0.085	+0.080	<.001	<.001	3	15
STAD	Mitochondrial membrane organization →	+0.095	+0.074	<.001	<.001	3	14
STAD	tRNA processing →	+0.082	+0.073	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,756 associations by consensus.

Mitochondrial gene expression by NRG1-IT1 expression — STAD

Explore this box plot interactively →