Across TCGA patient cohorts, NR2C2AP mutation is significantly associated with the RNA expression of many other genes, with 370 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NR2C2AP-associated genes across cancer lineages are OSBPL9P5, HMGN2P39, and PRPS1L1. Each is linked with NR2C2AP in more than 1 cancer types. Because this analysis shows association rather than direction, both NR2C2AP-to-partner and partner-to-NR2C2AP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2C2AP→partner) and Y-score (partner→NR2C2AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OSBPL9P5 →	+0.261	+7.040	<.001	<.001	3	2
COAD	HMGN2P39 →	+0.593	+4.173	<.001	.003	3	2
COAD	PRPS1L1 →	+0.208	+4.063	<.001	.005	3	2
COAD	NDUFS5P5 →	+0.375	+4.374	<.001	.002	3	2
COAD	RPS11P1 →	+0.327	+3.646	<.001	.009	3	2
COAD	SOD1P2 →	+0.280	+4.730	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 370 associations by consensus.

Exploration

NR2C2AP survival (RNA) · tumor vs normal (RNA) · all NR2C2AP data types