Across TCGA pan-cancer cohorts, NR2C2AP RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of NR2C2AP’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where NR2C2AP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NR2C2AP is over-expressed in tumor.
COAD, HNSC, and KIRC are the cancer types where NR2C2AP tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NR2C2AP RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.