NR1D1

Across TCGA patient cohorts, NR1D1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,730 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NR1D1-associated proteins across cancer lineages are APBB2, BIRC6_S3591, and PLCL2_S1113. Each is linked with NR1D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NR1D1-to-partner and partner-to-NR1D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR1D1 versus APBB2 in COAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NR1D1→partner) and Y-score (partner→NR1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	APBB2 →	+0.343	+0.852	.002	.001	3	4
PDAC	BIRC6_S3591 →	-0.449	-0.761	.003	<.001	3	4
LSCC	PLCL2_S1113 →	-0.460	-0.585	<.001	<.001	3	4
PDAC	HLA-DMA →	-0.636	-0.527	.007	.009	3	4
BRCA	KRT19 →	+0.714	+0.833	<.001	<.001	3	4
BRCA	SPCS3 →	-0.408	-0.892	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,730 associations by consensus.

NR1D1 vs APBB2 — COAD

Explore this scatter interactively →