NQO2

Across TCGA patient cohorts, NQO2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,395 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NQO2-associated proteins across cancer lineages are WRNIP1, RPRD2, and CDYL. Each is linked with NQO2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NQO2-to-partner and partner-to-NQO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NQO2 versus WRNIP1 in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NQO2→partner) and Y-score (partner→NQO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WRNIP1 →	+0.308	+0.488	<.001	<.001	3	5
LUAD	RPRD2 →	+0.207	+0.422	<.001	<.001	3	4
LSCC	CDYL →	+0.309	+0.634	<.001	<.001	3	4
LSCC	ARCN1 →	-0.190	-0.484	<.001	<.001	3	3
BRCA	PAK1IP1 →	+0.307	+0.446	.001	<.001	3	3
PDAC	CBFB →	+0.279	+0.436	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,395 associations by consensus.

NQO2 vs WRNIP1 — LSCC

Explore this scatter interactively →