NQO2

Across TCGA cell cohorts, NQO2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,578 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NQO2-associated genes across cancer lineages are IMPA2, PROS1, and ALOX5AP. Each is linked with NQO2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NQO2-to-partner and partner-to-NQO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NQO2 versus IMPA2 in LUNG_SCLC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NQO2→partner) and Y-score (partner→NQO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	IMPA2 →	+1.916	+1.541	.001	.006	3	4
LARGE_INTESTINE	PROS1 →	+2.045	+1.068	.007	.005	3	4
KIDNEY	ALOX5AP →	-1.233	-1.783	.007	.004	3	4
SKIN	ADO →	+0.631	+1.404	<.001	<.001	3	4
LUNG_NSCLC_LUAD	TMEM135 →	+0.857	+1.219	<.001	<.001	3	4
LUNG_NSCLC_LUAD	CIB1 →	+0.580	+0.733	.002	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,578 associations by consensus.

NQO2 vs IMPA2 — LUNG_SCLC

Explore this scatter interactively →