Across TCGA patient cohorts, NPY6R mutation is significantly associated with the RNA expression of many other genes, with 150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPY6R-associated genes across cancer lineages are IGKV1OR-2, FAM86C1P, and SMAD5-AS1. Each is linked with NPY6R in more than 1 cancer types. Because this analysis shows association rather than direction, both NPY6R-to-partner and partner-to-NPY6R results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY6R→partner) and Y-score (partner→NPY6R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1OR-2 →	+0.302	+2.978	<.001	.001	3	1
UCEC	FAM86C1P →	+0.472	+3.255	.002	.009	3	1
UCEC	SMAD5-AS1 →	+0.259	+3.655	<.001	.002	3	1
UCEC	HEPACAM →	+0.130	+3.734	.009	.001	3	1
UCEC	VAMP5 →	+1.047	+3.201	<.001	.009	3	1
UCEC	PTCRA →	+0.494	+3.234	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 150 associations by consensus.

Exploration

NPY6R survival (RNA) · tumor vs normal (RNA) · all NPY6R data types