Across TCGA pan-cancer cohorts, NPY6R RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated NPY6R data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NPY6R RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NPY6R expression acts as an unfavorable survival marker, although some lineages such as KIRC and COAD show a favorable association.
KIRC, COAD, and ACC are the cancer types where NPY6R RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.