Across TCGA patient cohorts, NPY4R mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NPY4R-associated genes across cancer lineages are MIR526B, CGB1, and RNU6-90P. Each is linked with NPY4R in more than 1 cancer types. Because this analysis shows association rather than direction, both NPY4R-to-partner and partner-to-NPY4R results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY4R→partner) and Y-score (partner→NPY4R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR526B →	+0.501	+5.292	<.001	.006	3	2
BRCA	CGB1 →	+0.039	+8.471	<.001	.005	3	1
UCEC	RNU6-90P →	+0.707	+3.927	.006	.007	3	1
UCEC	MIR7976 →	+0.699	+4.038	<.001	.004	3	1
BRCA	KRTAP19-4 →	+0.098	+8.471	<.001	.005	3	1
BRCA	MIR520A →	+1.132	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

NPY4R survival (RNA) · tumor vs normal (RNA) · all NPY4R data types