Across TCGA patient cohorts, NPY2R mutation is significantly associated with the RNA expression of many other genes, with 5,121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPY2R-associated genes across cancer lineages are CCDC15, TEX30, and CENPU. Each is linked with NPY2R in more than 3 cancer types. Because this analysis shows association rather than direction, both NPY2R-to-partner and partner-to-NPY2R results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY2R→partner) and Y-score (partner→NPY2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC15 →	+0.301	+2.354	.003	<.001	3	3
UCEC	TEX30 →	+0.535	+1.807	<.001	<.001	3	3
UCEC	CENPU →	+0.713	+2.082	<.001	<.001	3	3
UCEC	EME1 →	+0.480	+2.457	.001	.001	3	3
UCEC	SPATA2L →	+0.397	+1.807	<.001	<.001	3	3
UCEC	MIS18A →	+0.389	+1.378	.008	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,121 associations by consensus.

Exploration

NPY2R survival (RNA) · tumor vs normal (RNA) · all NPY2R data types