NPTX2

Across TCGA patient cohorts, NPTX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,020 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NPTX2-associated proteins across cancer lineages are SLC9A3R1_S280, MRPL43, and PRAF2. Each is linked with NPTX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NPTX2-to-partner and partner-to-NPTX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPTX2 versus SLC9A3R1_S280 in PDAC, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPTX2→partner) and Y-score (partner→NPTX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC9A3R1_S280 →	-1.439	-0.910	<.001	<.001	3	4
PDAC	MRPL43 →	-0.432	-0.484	<.001	.007	3	4
UCEC	PRAF2 →	+0.484	+1.292	.001	.001	3	3
BRCA	C1QTNF3 →	+1.069	+0.599	<.001	.002	3	3
HNSC	AEBP1 →	+0.668	+0.892	<.001	.001	3	3
BRCA	CNN3 →	+0.549	+0.587	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,020 associations by consensus.

NPTX2 vs SLC9A3R1_S280 — PDAC

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