NPTX2

Across TCGA patient cohorts, NPTX2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,707 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPTX2-associated genes across cancer lineages are BEX1, PPM1AP1, and GRM4. Each is linked with NPTX2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NPTX2-to-partner and partner-to-NPTX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPTX2 versus BEX1 in OV, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPTX2→partner) and Y-score (partner→NPTX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BEX1 →	+2.847	+1.071	.001	.008	3	3
UCEC	PPM1AP1 →	+1.211	+1.497	.001	.003	3	3
LSCC	GRM4 →	+0.887	+2.410	.003	.001	3	3
GBM	STXBP1 →	+1.168	+1.330	<.001	<.001	3	3
GBM	SLC6A17-AS1 →	+0.340	+0.978	<.001	<.001	3	3
CCRCC	PTPRN →	+1.203	+1.463	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,707 associations by consensus.

NPTX2 vs BEX1 — OV

Explore this scatter interactively →