NPTX2

Across TCGA cell cohorts, NPTX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,395 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NPTX2-associated GO terms across cancer lineages are Purine nucleotide biosynthetic process, Transport along microtubule, and Regulation of postsynaptic membrane potential. Each is linked with NPTX2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NPTX2-to-partner and partner-to-NPTX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleotide biosynthetic process grouped by NPTX2-low versus NPTX2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPTX2→partner) and Y-score (partner→NPTX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Purine nucleotide biosynthetic process →	+0.029	+1.876	.006	.004	3	6
LUNG_SCLC	Transport along microtubule →	+0.064	+2.547	<.001	.005	3	5
SKIN	Regulation of postsynaptic membrane potential →	-0.112	-1.922	<.001	.008	3	5
SKIN	Regulation of insulin secretion involved in cellular response to glucose stimulus →	-0.051	-1.356	.001	.009	3	5
SKIN	Cellular response to type I interferon →	+0.111	+1.834	<.001	<.001	3	5
SKIN	Nucleoside triphosphate metabolic process →	+0.077	+2.154	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,395 associations by consensus.

Purine nucleotide biosynthetic process by NPTX2 expression — SOFT_TISSUE

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