NPR2

Across TCGA patient cohorts, NPR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,014 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NPR2-associated proteins across cancer lineages are KANK2, LRP1, and EFEMP1. Each is linked with NPR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NPR2-to-partner and partner-to-NPR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPR2 versus KANK2 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPR2→partner) and Y-score (partner→NPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KANK2 →	+0.499	+0.659	<.001	<.001	3	6
BRCA	LRP1 →	+0.596	+0.700	<.001	<.001	3	6
CCRCC	EFEMP1 →	+0.777	+0.324	<.001	<.001	3	6
CCRCC	EFEMP2 →	+0.708	+0.438	<.001	<.001	3	6
HNSC	MAP1A_S1069 →	+1.101	+0.779	<.001	<.001	3	6
OV	MRPS5 →	-0.368	-0.903	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,014 associations by consensus.

NPR2 vs KANK2 — BRCA

Explore this scatter interactively →