NPM1P41

Across TCGA patient cohorts, NPM1P41 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,005 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPM1P41-associated GO terms across cancer lineages are Aerobic respiration, Establishment of protein localization to membrane, and Regulation of organelle assembly. Each is linked with NPM1P41 in more than 11 cancer types. Because this analysis shows association rather than direction, both NPM1P41-to-partner and partner-to-NPM1P41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by NPM1P41-low versus NPM1P41-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPM1P41→partner) and Y-score (partner→NPM1P41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Aerobic respiration →	+0.067	+0.254	.003	<.001	3	12
ESCA	Establishment of protein localization to membrane →	+0.060	+0.274	.001	<.001	3	11
ESCA	Regulation of organelle assembly →	+0.065	+0.224	.001	.001	3	11
ESCA	Positive regulation of protein modification by small protein conjugation or removal →	+0.071	+0.282	<.001	<.001	3	11
STAD	Positive regulation of protein catabolic process →	+0.050	+0.124	<.001	<.001	3	11
ESCA	Positive regulation of mitotic cell cycle →	+0.063	+0.155	.002	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,005 associations by consensus.

Aerobic respiration by NPM1P41 expression — ESCA

Explore this box plot interactively →