Q-omics provides the consensus-scored NPM1P41 profile across patient tissues and cancer cell-line models. NPM1P41 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, NPM1P41 is differentially expressed in 4, with the highest sampling consensus in UCEC. Additionally, NPM1P41 RNA expression shows 6,005 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KICH, UCEC, and STAD as cancer lineages where NPM1P41 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NPM1P41 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NPM1P41 survival associations across molecular data types. NPM1P41 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NPM1P41 RNA expression–survival associations across cancer types. High NPM1P41 expression shows unfavorable associations in KICH, OV, KIRP, PAAD and TGCT, but favorable associations in ESCA. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for NPM1P41 RNA expression.
This table summarizes NPM1P41 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for NPM1P41. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NPM1P41 shows lower tumor expression in KIRP and higher tumor expression in UCEC, PRAD and BRCA. The UCEC box plot shows higher NPM1P41 RNA expression in tumor versus normal tissue (log2 FC = +0.175, t-test p = .037).
This table shows molecular features associated with NPM1P41 in patient tissues and cancer cell lines. In patient samples, NPM1P41 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
