NPM1P41

Across TCGA pan-cancer cohorts, NPM1P41 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of NPM1P41’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where NPM1P41 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P41 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

UCEC, PRAD, and KIRP are the cancer types where NPM1P41 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P41 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.175	.037	2	view →
PRAD	All	All	+0.015	.042	2	view →
KIRP	Male	All	−0.022	.036	1	view →
BRCA	All	II,III,IV	+0.016	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

NPM1P41–UCEC

Open the UCEC breakdown →