Across TCGA pan-cancer cohorts, NPM1P11 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated NPM1P11 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NPM1P11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NPM1P11 expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.
KIRC, LUAD, and ACC are the cancer types where NPM1P11 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.