NPL

Across TCGA cell cohorts, NPL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,781 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NPL-associated GO terms across cancer lineages are Calcium ion transport, RNA 3'-end processing, and Regulation of myoblast fusion. Each is linked with NPL in more than 11 cancer types. Because this analysis shows association rather than direction, both NPL-to-partner and partner-to-NPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium ion transport grouped by NPL-low versus NPL-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPL→partner) and Y-score (partner→NPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Calcium ion transport →	-0.062	-1.543	.003	.001	3	12
BLOOD_Leukemia	RNA 3'-end processing →	+0.047	+1.289	.002	<.001	3	10
OESOPHAGUS	Regulation of myoblast fusion →	+0.110	+1.462	<.001	<.001	3	9
OESOPHAGUS	Ribose phosphate biosynthetic process →	+0.068	+1.261	.004	<.001	3	9
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.113	+1.546	<.001	<.001	3	9
STOMACH	Aerobic respiration →	+0.096	+1.270	<.001	.002	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,781 associations by consensus.

Calcium ion transport by NPL expression — LUNG_NSCLC_LUSC

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