NPAS2-AS1

Across TCGA patient cohorts, NPAS2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,815 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPAS2-AS1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Regulation of organelle assembly, and Regulation of post-translational protein modification. Each is linked with NPAS2-AS1 in more than 22 cancer types. Because this analysis shows association rather than direction, both NPAS2-AS1-to-partner and partner-to-NPAS2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by NPAS2-AS1-low versus NPAS2-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPAS2-AS1→partner) and Y-score (partner→NPAS2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA metabolic process →	+0.065	+0.340	.003	<.001	3	23
STAD	Regulation of organelle assembly →	+0.053	+0.235	<.001	<.001	3	22
ESCA	Regulation of post-translational protein modification →	+0.078	+0.377	<.001	<.001	3	22
ESCA	Positive regulation of post-translational protein modification →	+0.077	+0.488	<.001	<.001	3	22
ESCA	Regulation of DNA repair →	+0.054	+0.342	.001	<.001	3	22
STAD	Negative regulation of RNA splicing →	+0.058	+0.237	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,815 associations by consensus.

Positive regulation of DNA metabolic process by NPAS2-AS1 expression — ESCA

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