NOX1

Across TCGA patient cohorts, NOX1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,791 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NOX1-associated genes across cancer lineages are SEC14L2, MCAT, and PRMT5. Each is linked with NOX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOX1-to-partner and partner-to-NOX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOX1 versus SEC14L2 in COAD, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOX1→partner) and Y-score (partner→NOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SEC14L2 →	-0.568	-0.802	<.001	<.001	3	1
COAD	MCAT →	-0.538	-0.589	.001	.007	3	1
COAD	PRMT5 →	-0.614	-0.598	.001	.004	3	1
COAD	POLE2 →	-0.645	-0.550	.004	.004	3	1
COAD	CNIH1 →	-0.627	-0.686	<.001	<.001	3	1
COAD	CGRRF1 →	-0.418	-0.508	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,791 associations by consensus.

NOX1 vs SEC14L2 — COAD

Explore this scatter interactively →