NOTCH2NLA

Across TCGA patient cohorts, NOTCH2NLA mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOTCH2NLA-associated genes across cancer lineages are TSPY25P. Each is linked with NOTCH2NLA in more than 1 cancer types. Because this analysis shows association rather than direction, both NOTCH2NLA-to-partner and partner-to-NOTCH2NLA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY25P grouped by NOTCH2NLA-low versus NOTCH2NLA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOTCH2NLA→partner) and Y-score (partner→NOTCH2NLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSPY25P →	+0.094	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TSPY25P by NOTCH2NLA expression — UCEC

Explore this box plot interactively →