Across TCGA patient cohorts, NOS1AP mutation is significantly associated with the RNA expression of many other genes, with 2,911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOS1AP-associated genes across cancer lineages are SPRING1, EOLA1, and CYCSP27. Each is linked with NOS1AP in more than 2 cancer types. Because this analysis shows association rather than direction, both NOS1AP-to-partner and partner-to-NOS1AP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOS1AP→partner) and Y-score (partner→NOS1AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPRING1 →	+0.609	+2.823	<.001	.001	3	3
SKCM	EOLA1 →	+0.312	+2.093	.005	.003	3	3
LIHC	CYCSP27 →	+0.208	+5.447	<.001	.005	3	2
SKCM	APOOP3 →	+0.016	+3.212	<.001	.004	3	2
SKCM	MRPL46 →	+0.367	+2.604	.001	<.001	3	2
SKCM	MYL12BP1 →	+0.417	+3.597	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,911 associations by consensus.

Exploration

NOS1AP survival (RNA) · tumor vs normal (RNA) · all NOS1AP data types