Q-omics provides the consensus-scored APOOP3 profile across patient tissues and cancer cell-line models. APOOP3 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, APOOP3 RNA expression shows 5,647 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, and STAD as cancer lineages where APOOP3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes APOOP3 survival associations across molecular data types. APOOP3 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

APOOP3 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	MESO (36)	view →

This table ranks reproducible APOOP3 RNA expression–survival associations across cancer types. High APOOP3 expression shows unfavorable associations in MESO, UCS, STAD, ESCA, LUAD and SKCM. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for APOOP3 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.018	0.559	<.001	36	view →
UCS	OS	Tertile	II,III,IV	0.202	0.623	.019	36	view →
STAD	OS	Tertile	III,IV	0.448	0.653	.030	24	view →
ESCA	DFS	Tertile	All	0.232	0.773	.006	18	view →
LUAD	OS	Tertile	II,III,IV	0.161	0.677	.017	18	view →
SKCM	DFS	Tertile	II,III,IV	0.058	0.708	<.001	18	view →

Pink = unfavorable, green = favorable. all 8 lineages →

APOOP3-MESO (OS)

Kaplan–Meier survival curve for APOOP3 RNA expression in MESO: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with APOOP3 in patient tissues and cancer cell lines. In patient samples, APOOP3 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,647	STAD (5452)	view →
RNA	3,799	COAD (1817)	view →