APOOP3

Across TCGA patient cohorts, APOOP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,647 significant associations in total. STAD shows the largest number of these associations.

The most reproducible APOOP3-associated GO terms across cancer lineages are Response to UV-C, Peptidyl-lysine methylation, and Respiratory electron transport chain. Each is linked with APOOP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both APOOP3-to-partner and partner-to-APOOP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to UV-C grouped by APOOP3-low versus APOOP3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOOP3→partner) and Y-score (partner→APOOP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to UV-C →	+0.079	+0.057	<.001	<.001	3	5
ESCA	Peptidyl-lysine methylation →	+0.094	+0.039	<.001	.005	3	5
STAD	Respiratory electron transport chain →	+0.109	+0.049	<.001	<.001	3	5
ESCA	Positive regulation of protein modification by small protein conjugation or removal →	+0.122	+0.052	<.001	.005	2	6
ESCA	Cardiac muscle contraction →	+0.064	+0.033	<.001	<.001	3	5
STAD	Negative regulation of DNA recombination →	+0.076	+0.069	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,647 associations by consensus.

Response to UV-C by APOOP3 expression — STAD

Explore this box plot interactively →