NOP16

Across TCGA patient cohorts, NOP16 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,625 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOP16-associated proteins across cancer lineages are WDR74, WDR36, and SMC2. Each is linked with NOP16 in more than 8 cancer types. Because this analysis shows association rather than direction, both NOP16-to-partner and partner-to-NOP16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOP16 versus WDR74 in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP16→partner) and Y-score (partner→NOP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR74 →	+0.413	+0.617	<.001	<.001	3	9
BRCA	WDR36 →	+0.401	+0.433	<.001	<.001	3	8
LSCC	SMC2 →	+0.623	+0.553	<.001	<.001	3	8
BRCA	DDX21 →	+0.772	+0.562	<.001	<.001	3	8
LSCC	GEMIN5 →	+0.272	+0.495	<.001	<.001	3	8
BRCA	GTPBP4 →	+0.563	+0.488	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,625 associations by consensus.

NOP16 vs WDR74 — LSCC

Explore this scatter interactively →