NOP10

Across TCGA patient cohorts, NOP10 protein abundance is significantly associated with the RNA expression of many other genes, with 11,765 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOP10-associated genes across cancer lineages are LYVE1, FCAR, and GAS5. Each is linked with NOP10 in more than 4 cancer types. Because this analysis shows association rather than direction, both NOP10-to-partner and partner-to-NOP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOP10 versus LYVE1 in GBM, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP10→partner) and Y-score (partner→NOP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LYVE1 →	-1.441	-0.333	<.001	<.001	3	5
GBM	FCAR →	-0.843	-0.326	<.001	<.001	3	5
UCEC	GAS5 →	+0.608	+0.284	<.001	<.001	3	5
LSCC	CXCR1 →	-0.848	-0.319	<.001	<.001	3	5
CCRCC	FHL5 →	-0.920	-0.138	.002	.005	3	5
CCRCC	EMCN →	-0.900	-0.132	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,765 associations by consensus.

NOP10 vs LYVE1 — GBM

Explore this scatter interactively →