NOMO2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NOMO2 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOMO2-associated genes across cancer lineages are PRSS55, OR14I1, and OR51A4. Each is linked with NOMO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOMO2-to-partner and partner-to-NOMO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOMO2→partner) and Y-score (partner→NOMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCPRSS55 →+0.078+4.108<.001.00532
LUNG_NSCLC_LUSCOR14I1 →+0.133+4.108<.001.00532
SKINOR51A4 →+0.006+4.022<.001.00632
SKINKRTAP9-1 →+0.023+4.022<.001.00632
LUNG_NSCLC_LUADTEX33 →+0.022+4.681<.001.00332
LUNG_NSCLC_LUADKRTAP9-9 →+0.012+4.681<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

Exploration