NOC3L

Across TCGA patient cohorts, NOC3L mutation is significantly associated with the RNA expression of many other genes, with 1,663 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOC3L-associated genes across cancer lineages are LINC02706, RNF126, and OR5D3P. Each is linked with NOC3L in more than 1 cancer types. Because this analysis shows association rather than direction, both NOC3L-to-partner and partner-to-NOC3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02706 grouped by NOC3L-low versus NOC3L-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC3L→partner) and Y-score (partner→NOC3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02706 →	+0.042	+4.463	<.001	.003	3	2
UCEC	RNF126 →	+0.499	+2.354	<.001	<.001	3	2
COAD	OR5D3P →	+0.040	+4.332	.007	.006	3	2
COAD	RNU6-1242P →	+0.471	+3.280	<.001	.008	3	2
COAD	RPL7P29 →	+0.125	+2.893	.002	.008	3	2
COAD	CYCSP49 →	+0.118	+4.557	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,663 associations by consensus.

LINC02706 by NOC3L expression — BLCA

Explore this box plot interactively →