NMUR2

Across TCGA patient cohorts, NMUR2 mutation is significantly associated with the RNA expression of many other genes, with 3,712 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMUR2-associated genes across cancer lineages are CDCA4, RCC1, and UFD1. Each is linked with NMUR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NMUR2-to-partner and partner-to-NMUR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA4 grouped by NMUR2-low versus NMUR2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMUR2→partner) and Y-score (partner→NMUR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CDCA4 →	+0.332	+1.836	.002	.002	3	4
UCEC	RCC1 →	+0.422	+1.662	.003	.004	3	4
UCEC	UFD1 →	+0.317	+1.992	.001	<.001	3	4
SKCM	DYNC2I2 →	+0.426	+1.511	<.001	.002	3	4
SKCM	AMY1C →	+0.044	+2.961	.001	<.001	3	3
LUSC	DANT1 →	+0.666	+3.003	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,712 associations by consensus.

CDCA4 by NMUR2 expression — SKCM

Explore this box plot interactively →