NMNAT3

Across TCGA patient cohorts, NMNAT3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,743 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NMNAT3-associated genes across cancer lineages are RN7SKP124, CTSL, and USP30. Each is linked with NMNAT3 in more than 5 cancer types. Because this analysis shows association rather than direction, both NMNAT3-to-partner and partner-to-NMNAT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NMNAT3 versus RN7SKP124 in LSCC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMNAT3→partner) and Y-score (partner→NMNAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RN7SKP124 →	+1.011	+0.815	<.001	<.001	3	6
COAD	CTSL →	-1.013	-0.789	<.001	<.001	3	5
LSCC	USP30 →	+0.385	+0.478	<.001	<.001	3	5
HNSC	RALGPS1 →	+0.693	+0.388	<.001	<.001	3	5
COAD	MANF →	-0.712	-0.852	<.001	<.001	3	5
COAD	KCNH8 →	+0.952	+0.487	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,743 associations by consensus.

NMNAT3 vs RN7SKP124 — LSCC

Explore this scatter interactively →