NLRP13

Across TCGA patient cohorts, NLRP13 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,708 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NLRP13-associated GO terms across cancer lineages are Methylation, Regulation of transcription elongation by RNA polymerase II, and Positive regulation of DNA metabolic process. Each is linked with NLRP13 in more than 13 cancer types. Because this analysis shows association rather than direction, both NLRP13-to-partner and partner-to-NLRP13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by NLRP13-low versus NLRP13-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP13→partner) and Y-score (partner→NLRP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.057	+0.193	<.001	<.001	3	14
ESCA	Regulation of transcription elongation by RNA polymerase II →	+0.068	+0.233	<.001	<.001	3	13
ESCA	Positive regulation of DNA metabolic process →	+0.070	+0.150	<.001	.003	3	12
ESCA	Regulation of mRNA catabolic process →	+0.058	+0.208	<.001	.001	3	12
ESCA	DNA-templated transcription termination →	+0.058	+0.178	<.001	.007	2	13
ESCA	DNA-templated transcription elongation →	+0.077	+0.232	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,708 associations by consensus.

Methylation by NLRP13 expression — STAD

Explore this box plot interactively →