NLRP13

Across TCGA cell cohorts, NLRP13 RNA expression is significantly associated with the go_rna of many other GO terms, with 96 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NLRP13-associated GO terms across cancer lineages are Regulation of macroautophagy, Regulation of autophagosome assembly, and Positive regulation of blood vessel endothelial cell migration. Each is linked with NLRP13 in more than 3 cancer types. Because this analysis shows association rather than direction, both NLRP13-to-partner and partner-to-NLRP13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by NLRP13-low versus NLRP13-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP13→partner) and Y-score (partner→NLRP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of macroautophagy →	+0.046	+0.023	<.001	.008	3	4
BLOOD_Lymphoma	Regulation of autophagosome assembly →	+0.047	+0.022	<.001	.009	3	3
BLOOD_Lymphoma	Positive regulation of blood vessel endothelial cell migration →	+0.045	+0.022	.006	.009	3	3
LARGE_INTESTINE	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.119	+0.002	<.001	.006	3	2
CNS	Regulation of TORC1 signaling →	+0.046	+0.005	<.001	.009	3	2
BLOOD_Lymphoma	Positive regulation of macroautophagy →	+0.045	+0.035	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

Regulation of macroautophagy by NLRP13 expression — BLOOD_Lymphoma

Explore this box plot interactively →