Across TCGA patient cohorts, NLGN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,591 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NLGN3-associated proteins across cancer lineages are LRP1, CNRIP1, and TLN2. Each is linked with NLGN3 in more than 7 cancer types. Because this analysis shows association rather than direction, both NLGN3-to-partner and partner-to-NLGN3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NLGN3→partner) and Y-score (partner→NLGN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRP1 →	+0.481	+0.653	<.001	<.001	3	8
UCEC	CNRIP1 →	+0.529	+0.514	<.001	<.001	3	6
HNSC	TLN2 →	+0.509	+0.579	<.001	<.001	3	6
CCRCC	DCN →	+0.985	+0.300	<.001	.001	3	6
BRCA	GAS7 →	+0.525	+0.474	<.001	<.001	3	6
HNSC	SYNPO2_S363 →	+1.487	+0.554	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,591 associations by consensus.

Exploration

NLGN3 survival (RNA) · tumor vs normal (RNA) · all NLGN3 data types