NKX6-3

Across TCGA cell cohorts, NKX6-3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,007 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NKX6-3-associated GO terms across cancer lineages are Lens development in camera-type eye, Positive regulation of cell cycle phase transition, and Negative regulation of fatty acid transport. Each is linked with NKX6-3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NKX6-3-to-partner and partner-to-NKX6-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lens development in camera-type eye grouped by NKX6-3-low versus NKX6-3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX6-3→partner) and Y-score (partner→NKX6-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Lens development in camera-type eye →	-0.090	-0.611	<.001	.005	3	4
BLOOD_Lymphoma	Positive regulation of cell cycle phase transition →	+0.063	+0.621	<.001	.004	3	3
BLOOD_Lymphoma	Negative regulation of fatty acid transport →	-0.097	-0.833	.002	<.001	3	3
BLOOD_Lymphoma	Transposition →	+0.849	+1.079	<.001	.003	3	3
BLOOD_Lymphoma	Intraciliary retrograde transport →	+0.034	+0.504	.002	.005	2	4
BLOOD_Lymphoma	Negative regulation of T-helper cell differentiation →	-0.084	-0.656	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,007 associations by consensus.

Lens development in camera-type eye by NKX6-3 expression — BLOOD_Lymphoma

Explore this box plot interactively →