NKX6-3

Across TCGA cell cohorts, NKX6-3 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NKX6-3-associated genes across cancer lineages are C6orf118. Each is linked with NKX6-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKX6-3-to-partner and partner-to-NKX6-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by NKX6-3-low versus NKX6-3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX6-3→partner) and Y-score (partner→NKX6-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.102	+3.793	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

C6orf118 by NKX6-3 expression — LARGE_INTESTINE

Explore this box plot interactively →