NKX3-1

Across TCGA patient cohorts, NKX3-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,754 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NKX3-1-associated proteins across cancer lineages are MNDA, GAB1, and CASP4. Each is linked with NKX3-1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NKX3-1-to-partner and partner-to-NKX3-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKX3-1 versus MNDA in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX3-1→partner) and Y-score (partner→NKX3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MNDA →	+1.057	+0.615	<.001	<.001	3	4
GBM	GAB1 →	-0.422	-0.481	<.001	<.001	3	4
GBM	CASP4 →	+0.408	+0.422	<.001	<.001	3	3
GBM	COPZ2 →	+0.561	+0.545	<.001	<.001	3	3
PDAC	DOCK6 →	-0.247	-0.436	<.001	.005	3	3
GBM	DOK3 →	+0.518	+0.413	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,754 associations by consensus.

NKX3-1 vs MNDA — GBM

Explore this scatter interactively →