NKX3-1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NKX3-1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKX3-1-associated genes across cancer lineages are mv Endothelial cells. Each is linked with NKX3-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKX3-1-to-partner and partner-to-NKX3-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by NKX3-1-low versus NKX3-1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX3-1→partner) and Y-score (partner→NKX3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECmv Endothelial cells →-0.035-2.989.011.03711
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

mv Endothelial cells by NKX3-1 expression — UCEC

Box plot of mv Endothelial cells in NKX3-1-low vs NKX3-1-high samples in UCEC.

Explore this box plot interactively →

Exploration