Across TCGA patient cohorts, NKX2-5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,314 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NKX2-5-associated proteins across cancer lineages are MYO5A_S600, EIF3A, and FERMT2. Each is linked with NKX2-5 in more than 2 cancer types. Because this analysis shows association rather than direction, both NKX2-5-to-partner and partner-to-NKX2-5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX2-5→partner) and Y-score (partner→NKX2-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYO5A_S600 →	-0.598	-0.855	<.001	.002	3	3
HNSC	EIF3A →	-0.137	-0.481	.002	.003	3	3
OV	FERMT2 →	+0.467	+0.463	<.001	.006	3	3
OV	HSPG2 →	+0.454	+0.471	<.001	.005	3	3
BRCA	PLOD1 →	+0.557	+0.828	<.001	<.001	3	3
BRCA	SULT2B1 →	-0.609	-1.194	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,314 associations by consensus.

Exploration

NKX2-5 survival (RNA) · tumor vs normal (RNA) · all NKX2-5 data types