Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, NKX2-5 mutation is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. LUAD shows the largest number of these associations.
The most reproducible NKX2-5-associated genes across cancer lineages are MRPS5P3, MIR575, and GXYLT1P1. Each is linked with NKX2-5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKX2-5-to-partner and partner-to-NKX2-5 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (NKX2-5→partner) and Y-score (partner→NKX2-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.