NKX2-3

Across TCGA patient cohorts, NKX2-3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,078 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NKX2-3-associated proteins across cancer lineages are RPL5, RSL1D1, and RSU1. Each is linked with NKX2-3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NKX2-3-to-partner and partner-to-NKX2-3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKX2-3 versus RPL5 in OV, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX2-3→partner) and Y-score (partner→NKX2-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RPL5 →	-0.192	-0.210	.001	.003	3	3
OV	RSL1D1 →	-0.401	-0.182	<.001	.003	3	3
COAD	RSU1 →	+0.466	+0.754	.001	<.001	2	4
PDAC	SEPTIN2 →	+0.230	+0.583	.001	<.001	3	3
OV	SORBS3 →	+0.413	+0.228	.003	.001	3	3
OV	IRAG1 →	+0.652	+0.240	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,078 associations by consensus.

NKX2-3 vs RPL5 — OV

Explore this scatter interactively →