NKX2-3

Across TCGA cell cohorts, NKX2-3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,559 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NKX2-3-associated GO terms across cancer lineages are Cytoplasmic translation, Regulation of stem cell population maintenance, and rRNA metabolic process. Each is linked with NKX2-3 in more than 8 cancer types. Because this analysis shows association rather than direction, both NKX2-3-to-partner and partner-to-NKX2-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by NKX2-3-low versus NKX2-3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX2-3→partner) and Y-score (partner→NKX2-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cytoplasmic translation →	+0.114	+0.560	.003	.005	3	9
BONE	Regulation of stem cell population maintenance →	+0.051	+0.374	<.001	<.001	3	9
OESOPHAGUS	rRNA metabolic process →	+0.106	+0.400	.002	.007	2	9
OESOPHAGUS	Nucleoside phosphate biosynthetic process →	+0.055	+0.502	<.001	<.001	3	8
BONE	Protein-RNA complex assembly →	+0.135	+0.449	<.001	<.001	3	8
OESOPHAGUS	Purine ribonucleoside triphosphate metabolic process →	+0.115	+0.546	.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,559 associations by consensus.

Cytoplasmic translation by NKX2-3 expression — OESOPHAGUS

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