NKX2-1-AS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NKX2-1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,127 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NKX2-1-AS1-associated proteins across cancer lineages are TM2D3, TMEM135, and TMEM63B. Each is linked with NKX2-1-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKX2-1-AS1-to-partner and partner-to-NKX2-1-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKX2-1-AS1 versus TM2D3 in LUAD, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX2-1-AS1→partner) and Y-score (partner→NKX2-1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADTM2D3 →-0.768-0.671<.001.00632
LUADTMEM135 →+0.390+1.088<.001<.00132
LUADTMEM63B →+0.320+0.945.002.00232
LSCCTNIK_T581 →+0.633+0.529<.001<.00132
LUADTNS3_T632 →-0.697-0.602.002.00632
LUADTNS4_S350 →-1.547-1.137<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,127 associations by consensus.

NKX2-1-AS1 vs TM2D3 — LUAD

Per-sample scatter of NKX2-1-AS1 vs TM2D3 in LUAD (Pearson r = -0.42).

Explore this scatter interactively →

Exploration