Across TCGA patient cohorts, NKX1-2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,816 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NKX1-2-associated proteins across cancer lineages are RDH10, OAT, and PSME4. Each is linked with NKX1-2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NKX1-2-to-partner and partner-to-NKX1-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX1-2→partner) and Y-score (partner→NKX1-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RDH10 →	+0.953	+0.889	<.001	<.001	3	4
LUAD	OAT →	+0.878	+0.945	<.001	<.001	3	4
BRCA	PSME4 →	+0.371	+1.034	<.001	.002	3	4
BRCA	SRA1 →	-0.199	-0.842	<.001	<.001	3	3
BRCA	DENND2D →	-0.504	-0.953	<.001	<.001	3	3
BRCA	DHRS3 →	+0.597	+0.891	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,816 associations by consensus.

Exploration

NKX1-2 survival (RNA) · tumor vs normal (RNA) · all NKX1-2 data types