Across TCGA cell cohorts, NKX1-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,283 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NKX1-2-associated GO terms across cancer lineages are Regulation of cytoplasmic translation, Negative regulation of RNA catabolic process, and Positive regulation of lung ciliated cell differentiation. Each is linked with NKX1-2 in more than 6 cancer types. Because this analysis shows association rather than direction, both NKX1-2-to-partner and partner-to-NKX1-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX1-2→partner) and Y-score (partner→NKX1-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of cytoplasmic translation →	+0.071	+0.508	.002	.007	3	7
STOMACH	Negative regulation of RNA catabolic process →	+0.068	+0.376	<.001	.008	3	7
LUNG_NSCLC_LUAD	Positive regulation of lung ciliated cell differentiation →	+1.005	+1.158	<.001	<.001	3	7
SKIN	Keratinocyte development →	-0.404	-0.839	<.001	.006	3	6
OESOPHAGUS	Cellular response to rapamycin →	+0.177	+1.587	.001	<.001	3	6
OESOPHAGUS	Establishment of RNA localization →	+0.141	+2.222	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,283 associations by consensus.

Exploration

NKX1-2 survival (RNA) · tumor vs normal (RNA) · all NKX1-2 data types